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长期单眼剥夺后猫视觉功能的恢复

Functional restoration of vision in the cat after long-term monocular deprivation.

作者信息

Smith D C

出版信息

Science. 1981 Sep 4;213(4512):1137-9. doi: 10.1126/science.7268422.

DOI:10.1126/science.7268422
PMID:7268422
Abstract

Recovery of visual acuity was studied in six long-term monocularly deprived cats after removal of the nondeprived eye or reverse lid suture. Although both manipulations improved visual acuity, removal of the nondeprived eye was associated with more rapid recovery and higher find acuity than in reverse suture. These results are in agreement with the known electrophysiological effects of these recovery conditions and are also similar to the effects of reverse occlusion or loss of the nonamblyopic eye in human amblyopes.

摘要

在六只长期单眼剥夺的猫中,研究了在摘除未被剥夺的眼睛或进行反向眼睑缝合后视力的恢复情况。尽管这两种操作都改善了视力,但与反向缝合相比,摘除未被剥夺的眼睛与更快的恢复速度和更高的最终视力相关。这些结果与这些恢复条件已知的电生理效应一致,并且也类似于人类弱视患者中反向遮盖或非弱视眼丧失的效应。

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1
Functional restoration of vision in the cat after long-term monocular deprivation.长期单眼剥夺后猫视觉功能的恢复
Science. 1981 Sep 4;213(4512):1137-9. doi: 10.1126/science.7268422.
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Bilateral amblyopia after a short period of reverse occlusion in kittens.小猫短期反向遮盖后出现双侧弱视。
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The extent of visual recovery from early monocular or binocular visual deprivation in kittens.小猫早期单眼或双眼视觉剥夺后视觉恢复的程度。
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The permanence of the visual recovery that follows reverse occlusion of monocularly deprived kittens.单眼剥夺小猫反向遮盖后视觉恢复的持久性。
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Retinal and Optic Nerve Integrity Following Monocular Inactivation for the Treatment of Amblyopia.单眼失活治疗弱视后的视网膜和视神经完整性
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Adult visual experience promotes recovery of primary visual cortex from long-term monocular deprivation.成年期的视觉体验可促进初级视觉皮层从长期单眼剥夺中恢复。
Learn Mem. 2007 Aug 29;14(9):573-80. doi: 10.1101/lm.676707. Print 2007 Sep.
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Bidirectional modifications of visual acuity induced by monocular deprivation in juvenile and adult rats.幼年和成年大鼠单眼剥夺引起的视力双向改变。
J Neurosci. 2006 Jul 12;26(28):7368-74. doi: 10.1523/JNEUROSCI.0124-06.2006.
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Two step recovery of vision in the amblyopic eye after visual loss and enucleation of the fixing eye.在视力丧失和注视眼摘除后弱视眼视力的两步恢复。
Br J Ophthalmol. 1994 Jun;78(6):506-7. doi: 10.1136/bjo.78.6.506.