Füzi M
Zentralbl Bakteriol A. 1981;249(2):242-6.
The in vitro antibacterial activity of metronidazole was tested against 70 strains of aerobic vibrios (V. cholerae biotype cholerae, V. cholerae biotype eltor, NAG-vibrios, V. parahaemolyticus, v. alginolyticus) and 30 strains of microaerophilic Campylobacter (C. fetus subsp. fetus, C. fetus subsp. intestinalis and C. fetus subsp. jejuni). All strains of aerobic vibrios proved to be resistant (MIC 100 micrograms/ml) in contrast to campylobacter strains which were sensitive (MIC 1-4 micrograms/ml) to the drug. The findings confirm that metronidazole can be considered to be a selective inhibitor of anaerobic microorganisms, but its action is not restricted to obligate anaerobes.
测试了甲硝唑对70株需氧弧菌（霍乱弧菌霍乱生物型、霍乱弧菌埃尔托生物型、非典型弧菌、副溶血性弧菌、溶藻弧菌）和30株微需氧弯曲杆菌（胎儿弯曲杆菌胎儿亚种、胎儿弯曲杆菌肠道亚种和胎儿弯曲杆菌空肠亚种）的体外抗菌活性。与对该药敏感（MIC为1 - 4微克/毫升）的弯曲杆菌菌株相比，所有需氧弧菌菌株均表现出耐药性（MIC为100微克/毫升）。这些发现证实甲硝唑可被视为厌氧微生物的选择性抑制剂，但其作用并不局限于专性厌氧菌。
