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通过树脂血液灌注从肝衰竭患者体内清除胆红素。

Bilirubin removal from an hepatic failure patient by resin hemoperfusion.

作者信息

Mor L, Sideman S, Mihich M, Taitelman U

出版信息

Int J Artif Organs. 1981 May;4(3):146-7.

PMID:7275344
Abstract

An hemoperfusion (HP) column, packed with beads of a macroreticular MR ion exchange resin which were made biocompatible by coating with a fine layer of cross-linked human albumin, was applied to the removal of bilirubin (BIL) from a jaundiced 69-year old man with hepatic failure. The column was found most suitable for BIL removal. However, the high volumetric mass transfer coefficient of the unconjugated (UC) BIL indicates that this column could best be used for BIL removal from babies suffering from unconjugated hyperbilirubinemia.

摘要

一个血液灌流(HP)柱,填充有大孔MR离子交换树脂珠,通过涂覆一层交联人白蛋白使其具有生物相容性,用于从一名69岁肝功能衰竭的黄疸患者中去除胆红素(BIL)。发现该柱最适合去除BIL。然而,未结合(UC)BIL的高体积传质系数表明,该柱最适合用于从患有未结合型高胆红素血症的婴儿中去除BIL。

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