Worth G K, Retallack R W, Gutteridge D H
J Endocrinol Invest. 1981 Apr-Jun;4(2):233-6. doi: 10.1007/BF03350459.
Biologically inactive thyroid stimulating hormone (TSH) has been reported in hypothyroid patients. We report the first case of immunoreactive, but abnormal TSH in a euthyroid patient following hypophysectomy for a prolactin secreting pituitary adenoma. Indirect evidence indicates that this abnormal TSH was biologically inactive. The TSH was characterized by gel chromatography and has a molecular weight of approximately 23,000 daltons.
甲状腺功能减退患者中曾有生物学无活性的促甲状腺激素（TSH）的报道。我们报告了第一例在因分泌催乳素的垂体腺瘤行垂体切除术后甲状腺功能正常的患者中出现免疫反应性但异常的TSH的病例。间接证据表明这种异常的TSH在生物学上无活性。通过凝胶色谱法对该TSH进行了表征，其分子量约为23,000道尔顿。
