Polna I, Cendrowski W
J Neurol. 1977 Nov 1;216(4):301-10. doi: 10.1007/BF00314054.
Significantly higher CSF titers of hemagglutination (HI) measles virus antibody were found in 22 patients with subacute sclerosing panencephalitis (SSPE) and more elevated titers of measles virus neutralization (NV) antibody were encountered in 19 patients with SSPE than in 50 children and young adults with other neurological diseases. Similar differences occurred in the sera of patients and controls. The serum: CSF antibody ratio was examined in 15 SSPE cases. All but one patient showed reduced antibody ratio (less than 80) as compared with the normal index. In addition, serological studies in some SSPE patients showed the presence of CSF antimeasles fluorescent (FA) and mixed hemadsorption (HAd) antibodies as well as serum anti-ribonucleoprotein antibody (RNP), HAd and FA had titers from 1:16 to 1:32000. SSPE patients harbored serum antibodies against three components of the measles virus as measles patients did. Most of SSPE patients had increasing CSF and serum titers of measles-like virus antibodies over the course of the disease.
在22例亚急性硬化性全脑炎（SSPE）患者中，发现其脑脊液血凝（HI）麻疹病毒抗体滴度显著高于50例患有其他神经系统疾病的儿童和青年。19例SSPE患者的麻疹病毒中和（NV）抗体滴度比上述50例儿童和青年更高。患者和对照的血清中也出现了类似差异。对15例SSPE病例的血清：脑脊液抗体比值进行了检测。除1例患者外，所有患者的抗体比值均低于正常指标（小于80）。此外，对部分SSPE患者的血清学研究显示，脑脊液中存在抗麻疹荧光（FA）和混合血细胞吸附（HAd）抗体，血清中存在抗核糖核蛋白抗体（RNP），HAd和FA的滴度为1:16至1:32000。与麻疹患者一样，SSPE患者血清中也含有针对麻疹病毒三种成分的抗体。在疾病过程中，大多数SSPE患者脑脊液和血清中的类麻疹病毒抗体滴度不断升高。
