Abdelnoor A M, Dhib-Jalbut S S, Haddad F S
J Neuroimmunol. 1982 Jan;2(1):27-34. doi: 10.1016/0165-5728(82)90073-x.
Complement fixing (CF) antibody titers to measles, parainfluenza (PI) types 1 and 3, mumps, herpes type 1, and cytomegalovirus (CMV) in serum and cerebrospinal fluid (CSF) of 33 patients with subacute sclerosing panencephalitis (SSPE) were evaluated. Results were analyzed in comparison to 11 patients with neurological diseases other than SSPE and 7 normal subjects. All SSPE patients had elevated serum and CSF measles antibody titers. The number of SSPE patients manifesting elevated titers other than measles did not reach statistical significance when compared to controls, except for PI type 1. This suggests a possible dual infection with measles and PI in SSPE. The anticomplementary effect detected in the serum and CSF of some patients indirectly suggests the presence of immune complexes.
对33例亚急性硬化性全脑炎（SSPE）患者血清和脑脊液（CSF）中针对麻疹、1型和3型副流感病毒（PI）、腮腺炎、1型疱疹病毒和巨细胞病毒（CMV）的补体结合（CF）抗体滴度进行了评估。将结果与11例非SSPE的神经系统疾病患者和7名正常受试者进行了比较分析。所有SSPE患者的血清和脑脊液麻疹抗体滴度均升高。与对照组相比，除1型PI外，表现出除麻疹外滴度升高的SSPE患者数量未达到统计学意义。这表明SSPE中可能存在麻疹和PI的双重感染。在一些患者的血清和脑脊液中检测到的抗补体效应间接提示了免疫复合物的存在。
