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1
Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography.采用高压液相色谱法测定生物体液中甲硝唑及其两种主要代谢物。
Br J Clin Pharmacol. 1978 Nov;6(5):430-2. doi: 10.1111/j.1365-2125.1978.tb04608.x.
2
Determination of metronidazole and misonidazole and their metabolites in plasma and urine by high-performance liquid chromatography.高效液相色谱法测定血浆和尿液中的甲硝唑、米索硝唑及其代谢产物
J Chromatogr. 1978 Jul 1;146(1):163-6. doi: 10.1016/s0378-4347(00)81303-1.
3
Sensitive high-performance liquid chromatographic method for the determination of metronidazole and metabolites.用于测定甲硝唑及其代谢物的灵敏高效液相色谱法。
J Chromatogr. 1983 Oct 14;277:381-4. doi: 10.1016/s0378-4347(00)84862-8.
4
[HPLC determination of benzoylmetronidazole and metronidazole in biological materials].高效液相色谱法测定生物样品中苯甲酰甲硝唑和甲硝唑
Pharmazie. 1988 Jun;43(6):436.
5
Rapid determination of metronidazole in human serum and urine using a normal-phase high-performance liquid chromatographic column with aqueous solvents.使用带有水性溶剂的正相高效液相色谱柱快速测定人血清和尿液中的甲硝唑。
J Chromatogr. 1984 Aug 10;309(2):436-40. doi: 10.1016/0378-4347(84)80056-0.
6
Simultaneous determination of chloroquine and metronidazole in human biological fluid by high pressure liquid chromatography.高压液相色谱法同时测定人体生物体液中的氯喹和甲硝唑。
Life Sci. 1988;42(5):539-45. doi: 10.1016/0024-3205(88)90095-1.
7
Biologic activity of metronidazole in plasma and urine of volunteers with normal or impaired renal function.甲硝唑在肾功能正常或受损志愿者血浆及尿液中的生物活性。
Surgery. 1983 Jan;93(1 Pt 2):154-7.
8
[Simultaneous determination of seven sulfonamides and metronidazole and chloramphenicol in cosmetics by high performance liquid chromatography].高效液相色谱法同时测定化妆品中七种磺胺类药物、甲硝唑和氯霉素
Se Pu. 2007 Sep;25(5):743-6.
9
[Determination of common antibiotics and metronidazole in cosmetics by ultra performance liquid chromatography-tandem mass spectrometry].超高效液相色谱-串联质谱法测定化妆品中常见抗生素及甲硝唑
Se Pu. 2009 Jan;27(1):50-3.
10
Chromatographic methods for simultaneous determination of diiodohydroxyquinoline and metronidazole in their binary mixture.同时测定二碘羟基喹啉和甲硝唑二元混合物的色谱方法。
Pak J Pharm Sci. 2013 Sep;26(5):865-71.

引用本文的文献

1
Electrochemical Determination of Metronidazole in Tablet Samples Using Carbon Paste Electrode.使用碳糊电极电化学测定片剂样品中的甲硝唑。
J Anal Methods Chem. 2016;2016:3612943. doi: 10.1155/2016/3612943. Epub 2016 Mar 29.
2
In vitro susceptibility of Helicobacter pylori to several antimicrobial combinations.幽门螺杆菌对几种抗菌药物组合的体外敏感性
Antimicrob Agents Chemother. 1993 May;37(5):1184-6. doi: 10.1128/AAC.37.5.1184.
3
A rapid and specific semi-micro method involving high-pressure liquid chromatography for the assay of metronidazole in plasma, saliva, serum, urine and whole blood.一种快速且特异的半微量方法，该方法涉及高压液相色谱法，用于测定血浆、唾液、血清、尿液和全血中的甲硝唑。
Br J Clin Pharmacol. 1980 May;9(5):528-9. doi: 10.1111/j.1365-2125.1980.tb05856.x.
4
Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects.甲硝唑和替硝唑的液相色谱测定法：人体药代动力学和代谢研究
Antimicrob Agents Chemother. 1981 May;19(5):754-60. doi: 10.1128/AAC.19.5.754.
5
Disposition of oral metronidazole in hepatic cirrhosis and in hepatosplenic schistosomiasis.口服甲硝唑在肝硬化和肝脾血吸虫病中的处置情况。
Gut. 1982 Oct;23(10):807-13. doi: 10.1136/gut.23.10.807.
6
A comparison of the pharmacokinetics of metronidazole in man after oral administration of single doses of benzoylmetronidazole and metronidazole.单次口服苯甲酰甲硝唑和甲硝唑后人体中甲硝唑药代动力学的比较。
Br J Clin Pharmacol. 1982 Aug;14(2):201-6. doi: 10.1111/j.1365-2125.1982.tb01962.x.
7
Clinical pharmacokinetics of metronidazole.甲硝唑的临床药代动力学
Clin Pharmacokinet. 1983 Jan-Feb;8(1):43-62. doi: 10.2165/00003088-198308010-00003.
8
Capillary agar diffusion assay for measuring metronidazole in human gingival crevice fluid.用于测量人龈沟液中甲硝唑的毛细管琼脂扩散试验。
Antimicrob Agents Chemother. 1982 May;21(5):836-7. doi: 10.1128/AAC.21.5.836.
9
Pharmacokinetics of metronidazole in patients with varying degrees of renal failure.甲硝唑在不同程度肾衰竭患者中的药代动力学
Br J Clin Pharmacol. 1985 Feb;19(2):203-9. doi: 10.1111/j.1365-2125.1985.tb02632.x.
10
Disposition of metronidazole and its effects on sulphasalazine metabolism in patients with inflammatory bowel disease.甲硝唑在炎症性肠病患者中的处置及其对柳氮磺胺吡啶代谢的影响。
Br J Clin Pharmacol. 1986 Apr;21(4):431-5. doi: 10.1111/j.1365-2125.1986.tb05218.x.

本文引用的文献

1
The isolation and identification of the urinary oxidative metabolites of metronidazole in man.人体中甲硝唑尿液氧化代谢物的分离与鉴定。
J Pharmacol Exp Ther. 1968 Jun;161(2):373-81.
2
Determination of therapeutic levels of metronidazole in plasma by gas-liquid chromatography.用气相色谱法测定血浆中甲硝唑的治疗浓度。
J Chromatogr. 1973 Dec 19;87(2):491-7. doi: 10.1016/s0021-9673(01)91751-0.
3
Microbiological agar diffusion assay for metronidazole concentrations in serum.血清中甲硝唑浓度的微生物琼脂扩散测定法。
Antimicrob Agents Chemother. 1974 May;5(5):466-8. doi: 10.1128/AAC.5.5.466.
4
GLC analysis of metronidazole in human plasma.人血浆中甲硝唑的气相色谱分析。
J Pharm Sci. 1975 Jun;64(6):1048-9. doi: 10.1002/jps.2600640642.
5
Use of high-pressure liquid chromatography to determine plasma levels of metronidazole and metabolites after intravenous administration.采用高压液相色谱法测定静脉给药后甲硝唑及其代谢物的血浆水平。
Antimicrob Agents Chemother. 1978 Feb;13(2):205-9. doi: 10.1128/AAC.13.2.205.

Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography.

作者信息

Gulaid A, Houghton G W, Lewellen O R, Smith J, Thorne P S

出版信息

Br J Clin Pharmacol. 1978 Nov;6(5):430-2. doi: 10.1111/j.1365-2125.1978.tb04608.x.

DOI:10.1111/j.1365-2125.1978.tb04608.x
PMID:728287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1429550/
Abstract
摘要