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早期和延迟纤维支气管镜检查在咯血患者中的临床疗效

Clinical efficacy of early and delayed fiberoptic bronchoscopy in patients with hemoptysis.

作者信息

Gong H, Salvatierra C

出版信息

Am Rev Respir Dis. 1981 Sep;124(3):221-5. doi: 10.1164/arrd.1981.124.3.221.

Abstract

We analyzed the records of 129 consecutive patients with hemoptysis to evaluate whether or not early (during hemoptysis or during the 48 h after hemoptysis stopped) fiberoptic bronchoscopy (FB) more frequently localized and/or diagnosed the source of bleeding and influenced clinical outcome than delayed FB (48 h or more after hemoptysis stopped). Patients were divided into 3 groups on the basis of their final diagnoses: neoplasm (31 patients), bronchitis/bronchiectasis (52 patients), and miscellaneous (46 patients). Although the likelihood of visualizing active bleeding (41 versus 8%) or its site (34 versus 11%) was significantly higher with early versus delayed FB, respectively, neither active bleeding nor a bleeding site were visualized in at least 60% of the 92 patients who underwent early FB. Definitive (endoscopic) diagnoses by early or delayed FB occurred primarily in patients with neoplasm. Clinical outcome based on the results of FB was not significantly different between the early and delayed groups. Thus, early, single FB was generally neither diagnostic nor therapeutically decisive in these patients with hemoptysis.

摘要

我们分析了129例连续性咯血患者的记录,以评估早期(咯血期间或咯血停止后的48小时内)纤维支气管镜检查(FB)在定位和/或诊断出血源方面是否比延迟纤维支气管镜检查(咯血停止后48小时或更长时间)更频繁,以及是否会影响临床结局。根据最终诊断将患者分为3组:肿瘤(31例患者)、支气管炎/支气管扩张(52例患者)和其他(46例患者)。尽管早期纤维支气管镜检查与延迟纤维支气管镜检查相比,分别观察到活动性出血(41%对8%)或其部位(34%对11%)的可能性显著更高,但在接受早期纤维支气管镜检查的92例患者中,至少60%的患者既未观察到活动性出血,也未观察到出血部位。早期或延迟纤维支气管镜检查的明确(内镜)诊断主要发生在肿瘤患者中。早期组和延迟组基于纤维支气管镜检查结果的临床结局无显著差异。因此,对于这些咯血患者,早期单次纤维支气管镜检查通常在诊断或治疗上都不具有决定性作用。

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