Latham C, Holzman P S, Manschreck T C, Tole J
Arch Gen Psychiatry. 1981 Sep;38(9):997-1003. doi: 10.1001/archpsyc.1981.01780340049006.
This study of two types of optokinetic nystagmus (OKN) provides evidence that previously reported pursuit impairments in schizophrenics may be due to a cortical dysfunction. Differences in responses to partial-field and full-field OKN stimuli strongly support the hypothesis that there are two functionally distinct but anatomically overlapping mechanisms that can produce nystagmus responses. Partial-field OKN is composed of alternating phases of pursuit and saccadic movements. The slow phases of partial-field OKN, like pursuit eye movements, are of significantly poorer quality in schizophrenics compared with normal controls. Full-field OKN, however, is intact in both groups. Partial-field OKN is an improved test for pursuit abnormalities that reflect disturbances of nonvoluntary attention.
这项对两种视动性眼球震颤（OKN）的研究提供了证据，表明先前报道的精神分裂症患者的追踪障碍可能是由于皮质功能障碍所致。对部分视野和全视野OKN刺激的反应差异有力地支持了这样一种假说，即存在两种功能上不同但解剖结构上重叠的机制，它们可以产生眼球震颤反应。部分视野OKN由追踪和扫视运动的交替阶段组成。与正常对照组相比，精神分裂症患者的部分视野OKN的慢相，如同追踪眼球运动一样，质量明显较差。然而，两组的全视野OKN都是正常的。部分视野OKN是一种用于检测追踪异常的改进测试，这些异常反映了非随意注意的紊乱。
