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手术性和功能性半皮质切除大鼠的学习:补偿的初步研究

Learning in surgical and functional hemidecorticate rats: a preliminary study of compensation.

作者信息

Rose F D, Morgan S, Oakley D A, Plotkin H C

出版信息

Behav Brain Res. 1980 Feb;1(1):93-9. doi: 10.1016/0166-4328(80)90047-9.

DOI:10.1016/0166-4328(80)90047-9
PMID:7284082
Abstract

A case is made for the conjoint use of surgical and functional hemidecorticate preparations in the investigation of compensation. Direct comparison of the effects of surgical and functional hemidecortication in rats in an active runway avoidance learning situation is reported. Trials to successively higher avoidance criteria, total avoidance responses, longest runs of consecutive avoidance responses, response latencies and running times are compared. None of these measures reveal differences between the two types of hemidecorticate preparation, although compared with a normal group both hemidecorticate groups show a deficit. The implications of this finding in terms of the compensation issue are discussed.

摘要

本文提出在代偿研究中联合使用手术性和功能性半皮质切除制备方法的理由。报告了在主动跑道回避学习情境下对大鼠进行手术性和功能性半皮质切除效果的直接比较。比较了达到相继更高回避标准的试验、总回避反应、连续回避反应的最长次数、反应潜伏期和奔跑时间。尽管与正常组相比,两个半皮质切除组均表现出缺陷,但这些指标均未显示出两种半皮质切除制备方法之间的差异。讨论了这一发现对代偿问题的意义。

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