与口腔链球菌抗原发生反应的唾液免疫球蛋白A抗体：人类纵向研究
Salivary immunoglobulin A antibodies reacting with antigens from oral streptococci: longitudinal study in humans.
作者信息
Gahnberg L, Krasse B
出版信息
Infect Immun. 1981 Sep;33(3):697-703. doi: 10.1128/iai.33.3.697-703.1981.
Abstract
The salivary immunoglobulin A (IgA) activity to antigens from four common oral streptococci was analyzed in samples from five humans. From each individual, parotid and whole saliva were collected 12 times over a period of 4 months. In samples collected at different occasions, the salivary IgA activity varied considerably. The variations showed a covariation with the concentration of total IgA in the saliva samples. A covariation was also found between salivary IgA antibodies of different specificity. It is concluded that reference antigens, in combination with measurement of total IgA concentration, ought to be used when evaluating the salivary IgA response in humans.
摘要
对来自五名人类受试者的样本分析了唾液免疫球蛋白A（IgA）针对四种常见口腔链球菌抗原的活性。在4个月的时间里，从每个个体收集腮腺唾液和全唾液12次。在不同时间收集的样本中，唾液IgA活性差异很大。这些变化与唾液样本中总IgA的浓度呈协变关系。在不同特异性的唾液IgA抗体之间也发现了协变关系。得出的结论是，在评估人类唾液IgA反应时，应使用参考抗原并结合总IgA浓度的测量。
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