Salonen J T, Puska P, Kottke T E, Heinonen O P
Int J Epidemiol. 1981 Sep;10(3):203-10. doi: 10.1093/ije/10.3.203.
A random population sample from Eastern Finland was studied. Altogether approximately 12 000 persons aged 25 to 59 years were examined with participation rate of 92%. Smoking, high saturated fat diet, increased serum cholesterol and elevated blood pressure showed clustering among men but not among women. Smoking tended to cluster in men with high saturated fat intake and hypercholesterolaemia. Increased serum cholesterol clustered with high blood pressure among both men and women. This risk factor clustering may contribute to the exceptionally high coronary heart disease incidence among men in the area. The reverse was true for women: smoking was less prevalent among women with elevated blood pressure or high saturated fat intake and did not differ by serum cholesterol.
对来自芬兰东部的随机人群样本进行了研究。总共约12000名年龄在25至59岁之间的人接受了检查,参与率为92%。吸烟、高饱和脂肪饮食、血清胆固醇升高和血压升高在男性中呈现聚集现象,但在女性中未出现。吸烟倾向于在高饱和脂肪摄入和高胆固醇血症的男性中聚集。血清胆固醇升高在男性和女性中均与高血压聚集。这种危险因素的聚集可能导致该地区男性冠心病发病率异常高。女性情况则相反:在血压升高或高饱和脂肪摄入的女性中,吸烟的比例较低,且与血清胆固醇无关。