Mann P G, Pereira M S, Smith J W, Hart R J, Williams W O
J Hyg (Lond). 1981 Oct;87(2):191-200. doi: 10.1017/s0022172400069400.
A five year collaborative study of influenza in volunteer families from 1973-78 covered a period in which there were outbreaks every year but no major epidemics of influenza. Volunteers over the age of 15 years were bled before and after each of the five winters, and virus isolation was attempted from as many as possible when they reported episodes of illness. Children under 15 in the volunteer families were also swabbed when they were ill. Although most families experienced one or more attacks by influenza viruses, there was little transmission within families.
1973年至1978年,针对志愿家庭中的流感进行了一项为期五年的合作研究。在此期间,每年都有流感爆发,但没有大规模的流感流行。15岁以上的志愿者在五个冬季中的每个冬季前后都接受了采血,并且当他们报告患病时,尽可能多地尝试进行病毒分离。志愿家庭中15岁以下的儿童生病时也进行了拭子采样。虽然大多数家庭都经历了一次或多次流感病毒侵袭,但家庭内部的传播很少。