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Ethanol potentiation of methyl mercury toxicity: a preliminary report.

作者信息

Turner C J, Bhatnagar M K, Yamashiro S

出版信息

J Toxicol Environ Health. 1981 Mar-Apr;7(3-4):665-8. doi: 10.1080/15287398109530008.

DOI:10.1080/15287398109530008
PMID:7288907
Abstract

The ability of ethanol to affect hindlimb ataxia and body weight changes induced by methyl mercury was studied in rats. Animals treated with either water or ethanol increased in body weight during the experiment and showed no impairment of hindlimb movement. Rats treated with methyl mercury also increased in body weight but developed moderate hindlimb ataxia. Animals treated with ethanol and methyl mercury initially gained but subsequently lost weight and exhibited severe hindlimb ataxia. The results provide evidence that ethanol can potentiate methyl mercury toxicity in rats and, by implication, in humans.

摘要

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引用本文的文献

1
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Environ Health Perspect. 2000 Mar;108 Suppl 1(Suppl 1):29-56. doi: 10.1289/ehp.00108s129.
2
Methylmercury exposure and mortality in southern Japan: a close look at causes of death.日本南部甲基汞暴露与死亡率:深入探究死亡原因
J Epidemiol Community Health. 1986 Jun;40(2):181-5. doi: 10.1136/jech.40.2.181.
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Methylmercury toxicity in spontaneously hypertensive rats (SHR).
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