Hull S M, Mackintosh A
Lancet. 1977 Nov 19;2(8047):1054-5. doi: 10.1016/s0140-6736(77)91886-4.
All 24 patients on long-term digoxin in a general practice were reviewed. 17 of the 18 patients in sinus rhythm had their digoxin discontinued without any alteration in their cardiovascular signs or symptoms. Other therapy was adjusted as necessary. These results suggest that heart-failure can often be managed without long-term digoxin therapy.