de Wildt D J, Porsius A J, van Rooy H H
J Chromatogr. 1981 Oct 9;225(2):381-6. doi: 10.1016/s0378-4347(00)80286-8.
A high-performance liquid chromatographic method, based on a dynamic cation-exchange system was used for the determination of physostigmine in brain tissue extracts. The precision and detection limit of the method as well as the extraction efficiency were established. The distribution of physostigmine over several parts of the brain after intravertebral application is reported.
采用基于动态阳离子交换系统的高效液相色谱法测定脑组织提取物中的毒扁豆碱。确定了该方法的精密度、检测限以及提取效率。报道了经椎间给药后毒扁豆碱在脑的几个部位的分布情况。
