Owens O M, Ryan K J, Tulchinsky D
J Clin Endocrinol Metab. 1981 Dec;53(6):1307-9. doi: 10.1210/jcem-53-6-1307.
The serum concentration of human chorionic gonadotropin (hCG) was measured at 10- to 60-minute intervals for 4-24 hours in 5 women at 5-8 weeks of pregnancy. hCG was found to be secreted episodically with pulses observed every 2-4 hours. The episodic secretion of hCG may have important implications to our understanding of both normal and abnormal reproduction.
对5名怀孕5至8周的女性,在4至24小时内每隔10至60分钟测量一次血清人绒毛膜促性腺激素(hCG)浓度。发现hCG呈间歇性分泌,每2至4小时出现一次脉冲。hCG的间歇性分泌可能对我们理解正常和异常生殖都具有重要意义。