Dean G, Goodall J, Downie A
J Epidemiol Community Health. 1981 Jun;35(2):110-3. doi: 10.1136/jech.35.2.110.
Multiple sclerosis has been reported to have a high prevalence in the Orkney and Shetland Islands and in Caithness in comparison with the highlands of Scotland and the Outer Hebrides-the Western Isles. For this reason a survey was undertaken in the Outer Hebrides and 25 probable and 30 probable and possible patients with multiple sclerosis were found. This is an increase from eight and 11 respectively found in 1954. The present prevalence rate of 97.3 per 100 000 for probable and possible multiple sclerosis is not significantly different from that found in a recent study in the Grampian region in north-east Scotland. Repeated studies in small populations generally show increasing prevalence of multiple sclerosis because some patients are missed in the earlier studies, and over a long period of time there may also be some increase in survival time. This increase has been found in the Orkney and Shetland Islands, in north-east Scotland, and also in the Outer Hebrides.
据报道,与苏格兰高地和外赫布里底群岛(西部群岛)相比,多发性硬化症在奥克尼群岛、设得兰群岛和凯斯内斯郡的患病率较高。因此,在外赫布里底群岛进行了一项调查,发现了25例可能患有多发性硬化症的患者以及30例可能或疑似患有多发性硬化症的患者。这一数字相比1954年分别发现的8例和11例有所增加。目前,每10万人中可能或疑似患有多发性硬化症的患病率为97.3,与最近在苏格兰东北部格兰扁地区的一项研究结果没有显著差异。在小群体中反复进行的研究通常表明,多发性硬化症的患病率在上升,这是因为在早期研究中会遗漏一些患者,而且在很长一段时间内,患者的存活时间可能也会有所增加。这种患病率的上升在奥克尼群岛、设得兰群岛、苏格兰东北部以及外赫布里底群岛都有发现。