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不同丙酸杆菌菌株免疫刺激效力的比较研究。

Comparative study on the immunostimulatory potency of different Propionibacterium strains.

作者信息

Ko H L, Roszkowski W, Jeljaszewicz J, Pulverer G

出版信息

Med Microbiol Immunol. 1981;170(1):1-9. doi: 10.1007/BF02123791.

DOI:10.1007/BF02123791
PMID:7300800
Abstract

198 strains of Propionibacterium acnes, P. avidum, and P. granulosum were tested for their immunostimulatory potency using splenomegaly as index of stimulation, the activity differed widely from strain to strain. The antitumor and antimetastatic properties of six strains with differing stimulation activities were carefully examined. A close correlation between spleen enlargement and antitumor effects could be observed. The simple spleen enlargement test is recommended for determination of the immunopotency of propionibacteria and for the standardisation of vaccine preparations.

摘要

以脾肿大作为刺激指标，对198株痤疮丙酸杆菌、嗜丙酸杆菌和颗粒丙酸杆菌进行了免疫刺激效力测试，各菌株的活性差异很大。仔细研究了六种具有不同刺激活性的菌株的抗肿瘤和抗转移特性。可观察到脾肿大与抗肿瘤效果之间存在密切相关性。推荐使用简单的脾肿大试验来测定丙酸杆菌的免疫效力以及疫苗制剂的标准化。

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Comparative study on the immunostimulatory potency of different Propionibacterium strains.不同丙酸杆菌菌株免疫刺激效力的比较研究。
Med Microbiol Immunol. 1981;170(1):1-9. doi: 10.1007/BF02123791.
2
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引用本文的文献

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Clin Microbiol Rev. 2018 May 30;31(3). doi: 10.1128/CMR.00064-17. Print 2018 Jul.
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The influence of killed Propionibacterium granulosum on experimental infection with Escherichia coli.

本文引用的文献

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[STIMULATION OF THE PHAGOCYTIC ACTIVITY OF THE RETICULOENDOTHELIAL SYSTEM BY CORYNEBACTERIUM PARVUM].[短小棒状杆菌对网状内皮系统吞噬活性的刺激作用]
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The correlation of susceptibility of different Propionibacterium strains to macrophage killing and antitumor activity.不同丙酸杆菌菌株对巨噬细胞杀伤的敏感性与抗肿瘤活性之间的相关性。
Med Microbiol Immunol. 1980;169(1):1-8. doi: 10.1007/BF02123706.
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Qualitative and quantitative investigations on the resident bacterial skin flora in healthy persons and in the non-affected skin of patients with seborrheic Eczema.
死颗粒丙酸杆菌对大肠杆菌实验性感染的影响。
Med Microbiol Immunol. 1987;176(2):75-8. doi: 10.1007/BF00200677.
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Immunostimulating cell surface substance from Staphylococcus epidermidis strain ATCC-31432 prevents metastatic lung colonization in Balb/c-mice.来自表皮葡萄球菌菌株ATCC - 31432的免疫刺激细胞表面物质可防止Balb/c小鼠发生转移性肺定植。
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The role of hepatic lectins and the activity of the mononuclear phagocyte system in systemic Listeria monocytogenes infection in Balb/c mice.肝凝集素的作用及单核吞噬细胞系统的活性在Balb/c小鼠全身性单核细胞增生李斯特菌感染中的研究
Med Microbiol Immunol. 1988;177(1):47-9. doi: 10.1007/BF00190310.
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Augmented production of granulocyte-macrophage colony-stimulating factor and alpha/beta interferon in mice inoculated with heat-killed Corynebacterium liquefaciens.接种热灭活的解脲棒状杆菌的小鼠中粒细胞巨噬细胞集落刺激因子和α/β干扰素的产量增加。
Infect Immun. 1991 Mar;59(3):1032-6. doi: 10.1128/iai.59.3.1032-1036.1991.
对健康人群以及脂溢性湿疹患者未受影响皮肤的常驻细菌皮肤菌群进行定性和定量研究。
Arch Dermatol Res. 1980;268(3):297-312. doi: 10.1007/BF00404292.
4
A lung-colony assay to determine the radiosensitivity of cells of a solid tumour.一种用于确定实体瘤细胞放射敏感性的肺集落测定法。
Int J Radiat Biol Relat Stud Phys Chem Med. 1969 Jul;15(5):435-44. doi: 10.1080/09553006914550721.
5
Cell wall composition and deoxyribonucleic acid similarities among the anaerobic coryneforms, classical propionibacteria, and strains of Arachnia propionica.厌氧棒状杆菌、经典丙酸杆菌和丙酸蛛网菌菌株之间的细胞壁组成及脱氧核糖核酸相似性
J Bacteriol. 1972 Mar;109(3):1047-66. doi: 10.1128/jb.109.3.1047-1066.1972.
6
Corynebacterium parvum: a synonym for Propionibacterium acnes?短小棒状杆菌：痤疮丙酸杆菌的同义词？
J Gen Microbiol. 1974 Feb;80(2):433-42. doi: 10.1099/00221287-80-2-433.
7
Fermentative and serological studies on Propionibacterium acnes.痤疮丙酸杆菌的发酵及血清学研究
Appl Microbiol. 1973 Feb;25(2):222-9. doi: 10.1128/am.25.2.222-229.1973.
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Enhancement and depression of the antibody response in mice caused by Corynebacterium parvum.微小棒状杆菌引起的小鼠抗体反应的增强与抑制
Clin Exp Immunol. 1974 Jul;17(3):519-32.
9
Comparative studies on the cell wall composition of some anaerobic coryneforms of varying lympho-reticular stimulatory activity.对一些具有不同淋巴网状刺激活性的厌氧棒状杆菌细胞壁组成的比较研究。
Dev Biol Stand. 1977;38:115-20.
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Immunomodulation of host resistance to experimental viral infections in mice: effects of Corynebacterium acnes, Corynebacterium parvum, and Bacille calmette-guérin.小鼠对实验性病毒感染的宿主抵抗力的免疫调节：痤疮丙酸杆菌、短小棒状杆菌和卡介苗的作用。
J Infect Dis. 1977 May;135(5):763-70. doi: 10.1093/infdis/135.5.763.