Ando J, Kobayashi T, Miyamoto A, Tomita K, Yasuda H
Hokkaido Igaku Zasshi. 1978 Jul;53(4):283-5.
Using electromyographic techniques, we examined the possibility that idiopathic cardiomyopathy might be a cardiac manifestation of a general myopathy. The EMG studies were done on sixteen normal subjects and seventeen patients with idiopathic cardiomyopathy, including six with hypertrophic obstructive cardiomyopathy (HOCM), six with hypertrophic cardiomyopathy (HCM), and five with congestive cardiomyopathy (CCM). The action potential duration in the brachial biceps were determined exactly by a special recording technique. In the normal subjects, the mean action potential duration was 5.42 +/- 0.12 msec. In the patients with idiopathic cardiomyopathy, the mean action potential duration was 4.43 +/- 0.15 msec, which was significantly shorter than that of the normal subjects; 4.06 +/- 0.30 msec in HOCM, 4.45 +/- 0.20 msec in HCM, and 4.48 +/- 0.13 msec in CCM. These findings suggest that idiopathic cardiomyopathy is only one aspect of a larger disease spectrum, with abnormalities in both voluntary and cardiac muscles.
我们运用肌电图技术，研究了特发性心肌病可能是一种全身性肌病的心脏表现的可能性。对16名正常受试者和17名特发性心肌病患者进行了肌电图研究，其中包括6名肥厚性梗阻性心肌病（HOCM）患者、6名肥厚性心肌病（HCM）患者和5名充血性心肌病（CCM）患者。通过一种特殊的记录技术精确测定肱二头肌的动作电位持续时间。正常受试者的平均动作电位持续时间为5.42±0.12毫秒。特发性心肌病患者的平均动作电位持续时间为4.43±0.15毫秒，明显短于正常受试者；HOCM患者为4.06±0.30毫秒，HCM患者为4.45±0.20毫秒，CCM患者为4.48±0.13毫秒。这些发现表明，特发性心肌病只是更大疾病谱的一个方面，涉及随意肌和心肌的异常。
