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感染巴西日圆线虫期间大鼠小肠的推进活动

Propulsive activity of the rat small intestine during infection with the nematode Nippostrongylus brasiliensis.

作者信息

Farmer S G

出版信息

Parasite Immunol. 1981 Autumn;3(3):227-34. doi: 10.1111/j.1365-3024.1981.tb00402.x.

DOI:10.1111/j.1365-3024.1981.tb00402.x
PMID:7301408
Abstract

Intestinal propulsive motility was measured in rats infected with 4000 Nippostrongylus brasiliensis larvae by following the transit of radioactive chromium (51Cr) through the gut. On days 6, 8, 10, 12 and 14 post-infection, 51Cr was injected through an indwelling catheter into the duodenum. The animals were killed 15 min later and the distribution of radioactivity in the small intestine measured. A group of uninfected, catheterized animals served as controls. Intestinal propulsive activity was increased significantly on day 8 post-infection. No significant difference in the overall intestinal transit occurred on days 6, 10, 12 and 14 post-infection, although it appeared that it may have been decreased in the upper small intestine on day 6. The significance of these results is discussed.

摘要

通过追踪放射性铬(51Cr)在肠道中的转运,测定感染4000条巴西日圆线虫幼虫的大鼠的肠道推进性运动。在感染后的第6、8、10、12和14天,通过留置导管将51Cr注入十二指肠。15分钟后处死动物,测量小肠中放射性的分布。一组未感染的插管动物作为对照。感染后第8天肠道推进活性显著增加。感染后第6、10、12和14天,肠道整体转运没有显著差异,尽管在第6天小肠上段似乎有所下降。讨论了这些结果的意义。

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