牛血清白蛋白与PGBx（聚合15-酮基前列腺素B1）的相互作用。
Interaction of bovine serum albumin with PGBx (polymeric 15-keto-prostaglandin B1).
作者信息
Shmukler H W, Zawryt M G, Soffer E, Feely W, Polis E
出版信息
Physiol Chem Phys. 1981;13(3):241-50.
PMID:7301945
Abstract
Bovine serum albumin (BSA) interacts with PGBx, a polymeric derivative of 15-keto-prostaglandin B1, to form a complex that does not exhibit the fluorescence of free BSA. The complex is soluble at pH 5.2 in contrast to free PGBx, which is insoluble. Molar ratio of the BSA-PGBx complex is 1:18. This complexing appears to suppress the ability shown by non-complexed PGBx to reactivate phosphorylation in degraded isolated rat liver mitochondria.
摘要
牛血清白蛋白（BSA）与15-酮基前列腺素B1的聚合物衍生物PGBx相互作用，形成一种不显示游离BSA荧光的复合物。与不溶性的游离PGBx不同，该复合物在pH 5.2时可溶。BSA-PGBx复合物的摩尔比为1:18。这种络合作用似乎抑制了未络合的PGBx在降解的离体大鼠肝线粒体中重新激活磷酸化的能力。
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