Torhorst J
Schweiz Med Wochenschr. 1981 Sep 5;111(36):1319-21.
Inoculation of cell suspensions of a Ewing sarcoma (1.5 to 2.0 x 10(8) viable cells/mouse) into thymus less nude mice bred under conventional conditions gave a 90% take rate after subcutaneous injection and 35% after intraperitoneal. Intraperitoneal take rate is raised to 90% by intraperitoneal pretreatment with India ink. The same pretreatment shortens the tumor doubling time after subcutaneous inoculation. Both events are probably caused by inhibition of macrophages and/or natural killer cells.
将尤因肉瘤细胞悬液（1.5至2.0 x 10⁸个活细胞/小鼠）接种到在常规条件下饲养的无胸腺裸鼠中，皮下注射后的接种成功率为90%，腹腔注射后为35%。通过腹腔内预先注射印度墨水，腹腔接种成功率可提高到90%。同样的预处理可缩短皮下接种后的肿瘤倍增时间。这两个现象可能都是由巨噬细胞和/或自然杀伤细胞的抑制所导致的。
