Barinskii I F, Davydova A A, Karpovich L G, Bukovskaia S N
Vopr Virusol. 1981 Jul-Aug(4):434-8.
A long-term viremia (12 days postinoculation, the observation period) of both cellular and plasma type was detected in mice experimentally infected with tick-borne encephalitis virus, the Sophyin strain. Preliminary vaccination was found to prevent viremia in experimentally infected animals. Comparative studies of cellular and humoral immune responses in vaccinated mice showed the cellular immune responses to be most important in eliminating the virus upon subsequent experimental inoculation of mice with tick-borne encephalitis virus.
在用蜱传脑炎病毒索菲因株实验感染的小鼠中,检测到了细胞型和血浆型的长期病毒血症(接种后12天,观察期)。发现预先接种疫苗可预防实验感染动物出现病毒血症。对接种疫苗小鼠的细胞免疫和体液免疫反应进行的比较研究表明,在用蜱传脑炎病毒对小鼠进行后续实验接种时,细胞免疫反应在清除病毒方面最为重要。