雌激素诱导的过氧化物酶在大鼠子宫中的分布。
Distribution of oestrogen-induced peroxidase in the rat uterus.
作者信息
Affleck A, Keeping H S, Newcombe A M, Jellinck P H
出版信息
Acta Endocrinol (Copenh). 1981 Dec;98(4):609-13. doi: 10.1530/acta.0.0980609.
The activity of oestrogen-induced peroxidase in sections along the uterus of normal and mammary tumour-bearing adult rats was measured. Oestradiol increased the activity of this enzyme in the cervix as well as in other parts of the uterus in ovariectomized or immature rats. Peroxidase activity per mg protein was twice as high in the cervix as in the rest of the uterus where it was evenly distributed along both horns. The concentrations of oestrogen receptors in the cytosol and nucleus in each uterine horn and in the cervix was also determined and found to be lower in the cervix than in other sections of the uterus.
测量了正常成年大鼠和患乳腺肿瘤成年大鼠子宫各段中雌激素诱导过氧化物酶的活性。在去卵巢或未成熟大鼠中，雌二醇增加了该酶在子宫颈以及子宫其他部位的活性。每毫克蛋白质的过氧化物酶活性在子宫颈中是子宫其他部位的两倍，子宫其他部位沿两个子宫角均匀分布。还测定了每个子宫角和子宫颈中细胞质和细胞核中雌激素受体的浓度，发现子宫颈中的浓度低于子宫的其他部分。
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