一支马车队成员中爆发急性肺组织胞浆菌病。

Outbreak of acute pulmonary histoplasmosis in members of a wagon train.

作者信息

Gustafson T L, Kaufman L, Weeks R, Ajello L, Hutcheson R H, Wiener S L, Lambe D W, Sayvetz T A, Schaffner W

出版信息

Am J Med. 1981 Nov;71(5):759-65. doi: 10.1016/0002-9343(81)90361-2.

Abstract

In August 1980, an outbreak of acute pulmonary histoplasmosis occurred among participants in a wagon train as it traveled through eastern Tennessee. Of the 85 people on the train 69 (81 percent) had evidence of infection with Histoplasma capsulatum. Fifty-four people had symptomatic disease. The source of infection was traced to the site of a former winter blackbird roost in Charleston, Tennessee, that had been partially cleared five years earlier to make a park. Fourteen of 25 soil samples from this site were culture-positive for H. capsulatum. This is the first reported outbreak to involve a large migrant group. The outbreak is unusual in that exposure occurred without excavation, construction or tree-cutting at the site.

摘要

1980年8月，一列旅行货车队在穿越田纳西州东部时，车上的乘客中爆发了急性肺组织胞浆菌病。列车上的85人中有69人（81%）有感染荚膜组织胞浆菌的证据。54人出现了症状性疾病。感染源被追溯到田纳西州查尔斯顿一处以前的冬季黑鹂栖息地，该栖息地五年前已部分清理用作公园。该地点25份土壤样本中有14份荚膜组织胞浆菌培养呈阳性。这是首次报道涉及大型移民群体的疫情爆发。此次疫情不同寻常之处在于，感染发生时该地点并未进行挖掘、施工或砍伐树木等活动。