一名双相情感障碍患者在左旋多巴治疗期间出现快速心境循环发作。
Induction of rapid mood cycling during L-dopa treatment in a bipolar patient.
作者信息
Ko G N, Leckman J F, Heninger G R
出版信息
Am J Psychiatry. 1981 Dec;138(12):1624-5. doi: 10.1176/ajp.138.12.1624.
PMID:7304798
Abstract
The authors report a longitudinal case study of a woman with a history of bipolar affective disorder in which L-dopa shortened the manic-depressive cycle length when administered in a double-blind trial. This finding suggests a dopaminergic mechanism specifically in changing the frequency of cycling between depression and mania.
摘要
作者报告了一项针对一名有双相情感障碍病史女性的纵向病例研究，在双盲试验中给予左旋多巴时，其缩短了躁狂 - 抑郁周期的时长。这一发现提示了一种多巴胺能机制，特别是在改变抑郁和躁狂之间的循环频率方面。
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