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中性粒细胞的细胞色素b - 245也存在于人类单核细胞、巨噬细胞和嗜酸性粒细胞中。

Cytochrome b-245 of neutrophils is also present in human monocytes, macrophages and eosinophils.

作者信息

Segal A W, Garcia R, Goldstone H, Cross A R, Jones O T

出版信息

Biochem J. 1981 Apr 15;196(1):363-7. doi: 10.1042/bj1960363.

DOI:10.1042/bj1960363
PMID:7306076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1163001/
Abstract

A cytochrome b with a midpoint oxidation-reduction potential of -245mV (cytochrome b-245) that is a major component of the microbicidal oxidase system of human neutrophil leucocytes has been identified in human eosinophils, monocytes and macrophages at concentrations similar to that found in human neutrophils. It was absent from a variety of other cells. This cytochrome is present in phagocytic leucocytes and probably plays an important part in the specialized activities of these cells.

摘要

一种中点氧化还原电位为-245mV的细胞色素b（细胞色素b-245）已在人类嗜酸性粒细胞、单核细胞和巨噬细胞中被鉴定出来，它是人类中性粒细胞杀菌氧化酶系统的主要成分，其浓度与在人类中性粒细胞中发现的浓度相似。在多种其他细胞中未发现该物质。这种细胞色素存在于吞噬性白细胞中，可能在这些细胞的特殊活动中起重要作用。

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1
Cytochrome b-245 of neutrophils is also present in human monocytes, macrophages and eosinophils.中性粒细胞的细胞色素b - 245也存在于人类单核细胞、巨噬细胞和嗜酸性粒细胞中。
Biochem J. 1981 Apr 15;196(1):363-7. doi: 10.1042/bj1960363.
2
The enzymic reduction and kinetics of oxidation of cytochrome b-245 of neutrophils.中性粒细胞细胞色素b - 245的酶促还原及氧化动力学
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本文引用的文献

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THE DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES. MORPHOLOGY, CYTOCHEMISTRY, AND BIOCHEMISTRY.单核吞噬细胞的分化。形态学、细胞化学与生物化学
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Rapid incorporation of the human neutrophil plasma membrane cytochrome b into phagocytic vacuoles.人中性粒细胞质膜细胞色素b快速并入吞噬泡。
Biochem Biophys Res Commun. 1980 Jan 29;92(2):710-5. doi: 10.1016/0006-291x(80)90391-5.
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Absence of cytochrome b reduction in stimulated neutrophils from both female and male patients with chronic granulomatous disease.患有慢性肉芽肿病的女性和男性患者的受刺激中性粒细胞中细胞色素b还原缺失。
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A rapid single centrifugation step method for the separation of erythrocytes, granulocytes and mononuclear cells on continuous density gradients of Percoll.一种在Percoll连续密度梯度上分离红细胞、粒细胞和单核细胞的快速单步离心法。
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