Lipari G, Szabo A
Biochemistry. 1981 Oct 13;20(21):6250-6. doi: 10.1021/bi00524a053.
A variety of models incorporating internal motion, which can be used to extract information from nuclear magnetic resonance relaxation studies of deoxyribonucleic acid fragments, are formulated. Illustrative analyses of some recent multinuclear relaxation data are presented. Special emphasis is placed on determining whether the information extracted is unique. It is shown that the data are consistent with several physical pictures of the internal motion. However, all the models we have considered imply the existence of large-amplitude internal motions on the nanosecond time scale.
提出了多种包含内部运动的模型，这些模型可用于从脱氧核糖核酸片段的核磁共振弛豫研究中提取信息。给出了一些近期多核弛豫数据的示例分析。特别强调确定所提取的信息是否唯一。结果表明，这些数据与内部运动的几种物理图像一致。然而，我们所考虑的所有模型都意味着在纳秒时间尺度上存在大幅度的内部运动。
