对非洲锥虫抗性的遗传学：H-2基因座在决定对罗德西亚锥虫感染抗性中的作用。
Genetics of resistance to African trypanosomes: role of the H-2 locus in determining resistance to infection with Trypanosoma rhodesiense.
作者信息
Levine R F, Mansfield J M
出版信息
Infect Immun. 1981 Nov;34(2):513-8. doi: 10.1128/iai.34.2.513-518.1981.
Abstract
Susceptibility and resistance to Trypanosoma rhodesiense infections in inbred and H-2 congenic strains of mice were studied. Mean survival times and patterns of parasitemia were examined. C3HeB/FeJ mice were highly susceptible; CBA/J, A/J, and BALB/cByJ mice displayed an intermediate level of susceptibility; whereas C57BL/10 mice were highly resistant. H-2 congenic strains with the BL/10 background resembled the BL/10 parental type, thereby suggesting that the major histocompatibility complex does not play a major role in regulating resistance and susceptibility to infection with T. rhodesiense.
摘要
对近交系和H-2同源系小鼠感染罗德西亚锥虫的易感性和抗性进行了研究。检测了平均存活时间和寄生虫血症模式。C3HeB/FeJ小鼠高度易感；CBA/J、A/J和BALB/cByJ小鼠表现出中等易感性；而C57BL/10小鼠则高度抗性。具有BL/10背景的H-2同源系与BL/10亲本品系相似，因此表明主要组织相容性复合体在调节对罗德西亚锥虫感染的抗性和易感性方面不起主要作用。
相似文献
1
Genetics of resistance to African trypanosomes: role of the H-2 locus in determining resistance to infection with Trypanosoma rhodesiense.对非洲锥虫抗性的遗传学：H-2基因座在决定对罗德西亚锥虫感染抗性中的作用。
Infect Immun. 1981 Nov;34(2):513-8. doi: 10.1128/iai.34.2.513-518.1981.
2
3
4
5
Genetics of resistance to the African trypanosomes. IV. Resistance of radiation chimeras to Trypanosoma rhodesiense infection.
Cell Immunol. 1984 Aug;87(1):85-91. doi: 10.1016/0008-8749(84)90132-1.
6
The inheritance of factors controlling resistance in mice infected with Trypanosoma brucei rhodesiense.感染罗德西亚布氏锥虫的小鼠中控制抗性的因子的遗传。
J Parasitol. 1995 Aug;81(4):653-7.
7
Trypanosoma rhodesiense infection in mice: sex dependence of resistance.小鼠中的罗德西亚锥虫感染：抗性的性别依赖性。
Infect Immun. 1984 Jan;43(1):337-40. doi: 10.1128/iai.43.1.337-340.1984.
8
CpG oligodeoxynucleotide treatment enhances innate resistance and acquired immunity to African trypanosomes.CpG寡脱氧核苷酸治疗可增强对非洲锥虫的天然抵抗力和获得性免疫力。
Infect Immun. 2007 May;75(5):2366-73. doi: 10.1128/IAI.01649-06. Epub 2007 Mar 5.
9
African trypanosomes: inheritance of factors involved in resistance.
Exp Parasitol. 1989 Jul;69(1):1-8. doi: 10.1016/0014-4894(89)90164-1.
10
Genetic control of natural resistance to Trypanosoma rhodesiense: transfer of resistance with bone marrow or spleen cells.对罗德西亚锥虫天然抗性的遗传控制：通过骨髓或脾细胞转移抗性
J Infect Dis. 1985 May;151(5):911-6. doi: 10.1093/infdis/151.5.911.
引用本文的文献
1
Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.内林蛋白 A 鼠源化对宿主抵抗经口感染李斯特菌病的影响。
BMC Microbiol. 2013 Apr 23;13:90. doi: 10.1186/1471-2180-13-90.
2
Biological variation among african trypanosomes: I. Clonal expression of virulence is not linked to the variant surface glycoprotein or the variant surface glycoprotein gene telomeric expression site.非洲锥虫的生物学变异：I. 毒力的克隆表达与变异表面糖蛋白或变异表面糖蛋白基因端粒表达位点无关。
DNA Cell Biol. 2010 May;29(5):215-27. doi: 10.1089/dna.2009.0991.
3
CpG oligodeoxynucleotide treatment enhances innate resistance and acquired immunity to African trypanosomes.CpG寡脱氧核苷酸治疗可增强对非洲锥虫的天然抵抗力和获得性免疫力。
Infect Immun. 2007 May;75(5):2366-73. doi: 10.1128/IAI.01649-06. Epub 2007 Mar 5.
4
Interleukin-4-dependent immunoglobulin G1 isotype switch in the presence of a polarized antigen-specific Th1-cell response to the trypanosome variant surface glycoprotein.在对锥虫可变表面糖蛋白存在极化的抗原特异性Th1细胞应答的情况下，白细胞介素-4依赖性免疫球蛋白G1同种型转换。
Infect Immun. 1998 Feb;66(2):451-61. doi: 10.1128/IAI.66.2.451-461.1998.
5
Antibody responses induced by immunization of inbred mice susceptible and resistant to African trypanosomes.对非洲锥虫易感和有抗性的近交系小鼠免疫诱导的抗体反应。
Infect Immun. 1983 Jun;40(3):894-902. doi: 10.1128/iai.40.3.894-902.1983.
6
Immune responses to Candida albicans in genetically distinct mice.基因不同的小鼠对白色念珠菌的免疫反应。
Infect Immun. 1982 Dec;38(3):1020-8. doi: 10.1128/iai.38.3.1020-1028.1982.
7
Trypanosoma rhodesiense: analysis of the genetic control of resistance among mice.罗德西亚锥虫：小鼠抗药性遗传控制分析
Infect Immun. 1984 Apr;44(1):107-11. doi: 10.1128/iai.44.1.107-111.1984.
8
Trypanosoma rhodesiense infection in mice: sex dependence of resistance.小鼠中的罗德西亚锥虫感染：抗性的性别依赖性。
Infect Immun. 1984 Jan;43(1):337-40. doi: 10.1128/iai.43.1.337-340.1984.
9
Effect of splenectomy on Trypanosoma lewisi infection in young rats.脾切除术对幼鼠感染路氏锥虫的影响。
Infect Immun. 1983 Jun;40(3):1127-33. doi: 10.1128/iai.40.3.1127-1133.1983.
本文引用的文献
1
Parasitemia and survival in inbred strains of mice infected with Plasmodium berghei.
J Parasitol. 1957 Aug;43(4):413-9.
2
Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.使用二乙氨基乙基纤维素从人和其他哺乳动物中分离涎源性锥虫。
Exp Parasitol. 1970 Dec;28(3):521-34. doi: 10.1016/0014-4894(70)90120-7.
3
Genetic determinants of immunological responsiveness.免疫反应性的遗传决定因素。
Adv Immunol. 1974;18:1-66. doi: 10.1016/s0065-2776(08)60307-7.
4
The role of genetics in Gross virus leukemogenesis.遗传学在格罗斯病毒白血病发生中的作用。
Bibl Haematol. 1970(36):213-20. doi: 10.1159/000391710.
5
Histocompatibility-linked immune response genes.组织相容性连锁免疫反应基因
Science. 1972 Jan 21;175(4019):273-9. doi: 10.1126/science.175.4019.273.
6
Genetics of resistance to infection with Salmonella typhimurium in mice.小鼠对鼠伤寒沙门氏菌感染的抗性遗传学
J Infect Dis. 1976 Jan;133(1):72-8. doi: 10.1093/infdis/133.1.72.
7
Neutralizing antibody in Rodent Malaria.啮齿动物疟疾中的中和抗体。
Trans R Soc Trop Med Hyg. 1975;69(2):251-8. doi: 10.1016/0035-9203(75)90164-9.
8
9
Antigenic variation in trypanosomes.锥虫的抗原变异
Nature. 1978 Jun 22;273(5664):613-7. doi: 10.1038/273613a0.
10
Trypanosoma brucei: influence of host strain and parasite antigenic type on infections in mice.布氏锥虫：宿主品系和寄生虫抗原类型对小鼠感染的影响
Exp Parasitol. 1978 Apr;44(2):202-8. doi: 10.1016/0014-4894(78)90099-1.
Zotero 插件