Latman N S
J Rheumatol. 1981 Sep-Oct;8(5):725-9.
A literature survey revealed many reports implicating the microclimate and seasonal changes in arthritic diseases. Therefore, a retrospective study of the erythrocyte sedimentation rate (ESR) and the C-reactive protein (CRP) concentration of 2,802 rheumatoid arthritis (RA) was performed. No statistically significant fluctuation was found when analyzed according to the month of the year in which blood was taken. The significance of this is discussed in relation to other RA symptoms, meteorologic phenomena, microclimate, and the joint circulatory responses in RA. The observations reported are consistent with the concept that seasons and microclimate may affect some of the symptoms of RA, but not the inflammatory processes represented by the ESR and CRP.
一项文献调查显示，有许多报告表明关节炎疾病与微气候和季节变化有关。因此，对2802例类风湿性关节炎（RA）患者的红细胞沉降率（ESR）和C反应蛋白（CRP）浓度进行了回顾性研究。根据采血月份进行分析时，未发现有统计学意义的波动。结合类风湿性关节炎的其他症状、气象现象、微气候以及关节循环反应，对这一结果的意义进行了讨论。所报告的观察结果与季节和微气候可能影响类风湿性关节炎的某些症状，但不影响由ESR和CRP所代表的炎症过程这一概念相一致。
