Iliukhin A V, Burkovskaia T E
Kosm Biol Aviakosm Med. 1981 Nov-Dec;15(6):42-6.
The purpose of the investigation was to understand better the mechanisms of erythropoietic changes at the cellular level during a prolonged exposure to weightlessness. Following 96-, 140- and 175-day space flights cytokinetic and morphological changes in erythropoiesis were observed. The count of circulating erythrocytes decreased inflight and their life time reduced postflight. The shortening of the life time of erythrocytes postflight was paralleled by increased proliferative activity of erythroid cells. The erythrocytic balance was not reached as late as R + 36. It is recommended that the number of research methods be enlarged.
该研究的目的是更深入地了解在长期失重状态下细胞水平上红细胞生成变化的机制。在96天、140天和175天的太空飞行后，观察到红细胞生成的细胞动力学和形态学变化。飞行中循环红细胞数量减少，飞行后其寿命缩短。飞行后红细胞寿命的缩短与红系细胞增殖活性增加平行。直到R + 36时仍未达到红细胞平衡。建议扩大研究方法的数量。
