Rao C J, Shukla P K, Mohanty S, Reddy Y J
J Neurol Neurosurg Psychiatry. 1978 Oct;41(10):948-53. doi: 10.1136/jnnp.41.10.948.
Serum total lactate dehydrogenase (LDH) was estimated serially for up to 15 days in 110 patients with head injuries who had no extraneural injury. Increase in LDH activity generally indicated the degree of parenchymal brain damage. The prognostic value of LDH was established by correlating its activity with clinical criteria such as duration of unconsciousness and post-traumatic amnesia, type of brain damage, and quality of survival. A significant rise in LDH activity suggested severe brain damage and poor prognosis.
对110例无神经外损伤的头部受伤患者连续15天测定血清总乳酸脱氢酶（LDH）。LDH活性的升高通常表明脑实质损伤的程度。通过将LDH活性与诸如昏迷持续时间和创伤后遗忘症、脑损伤类型及生存质量等临床标准相关联，确定了LDH的预后价值。LDH活性显著升高提示严重脑损伤及预后不良。
