Thomas D G, Rowan T D
Injury. 1976 May;7(4):258-62. doi: 10.1016/s0020-1383(75)80003-9.
Serial levels of lactic dehydrogenase (LDH) isoenzymes have been measured in 92 neurosurgical patients with damaged brains, including 77 suffering from head injury. Serum LDH isoenzymes 1 and 2 rise in the injured group and generally reflect the degree of parenchymal brain damage. The method has possible diagnostic applications, as well as some prognostic use.