Hyvärinen L, Rovamo J, Laurinen P, Peltomaa A
Acta Ophthalmol (Copenh). 1981 Oct;59(5):763-73. doi: 10.1111/j.1755-3768.1981.tb08744.x.
Spatial contrast sensitivity functions of 11 retinitis pigmentosa patients were studied. The patients represented 3 different stages of the disease: 1: in the very severely impaired patients the contrast sensitivity and grating resolution had decreased to a fraction of normal. 2: in severely impaired patients, who had lost peripheral field but had subjectively satisfactory vision in the central field, contrast sensitivity differed considerably from one patient to another, 3: some of the moderately impaired patients, who still had useful peripheral vision, had nearly normal contrast sensitivity in the central vision while they already had large ring scotomas. The severity of reduction in contrast sensitivity was poorly correlated with visual acuity, the size of the visual field and the age of the patient. Because contrast sensitivity function cannot be predicted by means of other clinical measurements, it should be included in evaluation of visual impairment due to retinitis pigmentosa. We also measured contrast sensitivity at low luminance levels: this procedure provided useful information for evaluation of vision in retinitis pigmentosa. The contrast sensitivity function of each patient agreed with the subjective view of the patient about his visual impairment and it also corresponded with the examiners' evaluation of the patient's performance in different visual and visuomotor tasks.
对11名视网膜色素变性患者的空间对比敏感度函数进行了研究。这些患者代表了该疾病的3个不同阶段：1：在严重受损的患者中，对比敏感度和光栅分辨率已降至正常水平的一小部分。2：在严重受损的患者中，他们已经失去了周边视野，但中央视野的主观视力良好，不同患者之间的对比敏感度差异很大。3：一些中度受损的患者，他们仍有有用的周边视力，中央视力的对比敏感度接近正常，而他们已经有大的环形暗点。对比敏感度降低的严重程度与视力、视野大小和患者年龄的相关性较差。由于对比敏感度函数无法通过其他临床测量来预测，因此应将其纳入视网膜色素变性所致视力损害的评估中。我们还测量了低亮度水平下的对比敏感度：该程序为评估视网膜色素变性患者的视力提供了有用信息。每个患者的对比敏感度函数与患者对其视力损害的主观看法一致，也与检查者对患者在不同视觉和视觉运动任务中的表现评估一致。
