Brandt L, Boley S, Goldberg L, Mitsudo S, Berman A
Am J Gastroenterol. 1981 Sep;76(3):239-45.
The records of 81 patients with colitis whose symptoms began after the age of 50 years were analyzed to determine the importance of ischemia as a cause of colitis in this age group and to evaluate the accuracy of previous diagnoses. Patients were classified by clinical, roentgenological and pathologic criteria. A retrospective diagnosis of ischemic colitis was made in three-fourths of the patients, one-half of whom had original discharge diagnoses of ulcerative, Crohn's or nonspecific colitis. This study supports our belief that ischemia is the most common cause of colitis beginning in patients older than 50 years of age. Moreover, the incorrect diagnosis of idiopathic inflammatory bowel disease in a large proportion of these patients may explain why colitis has been reported to behave differently in the elderly than in the young.
对81例50岁以后出现症状的结肠炎患者的记录进行分析，以确定缺血作为该年龄组结肠炎病因的重要性，并评估先前诊断的准确性。根据临床、放射学和病理学标准对患者进行分类。四分之三的患者被回顾性诊断为缺血性结肠炎，其中一半患者最初出院诊断为溃疡性、克罗恩氏或非特异性结肠炎。这项研究支持了我们的观点，即缺血是50岁以上患者发生结肠炎的最常见原因。此外，这些患者中很大一部分被误诊为特发性炎症性肠病，这或许可以解释为何据报道结肠炎在老年人中的表现与年轻人不同。
