Franz H, Ziska P, Kindt A
Biochem J. 1981 May 1;195(2):481-4. doi: 10.1042/bj1950481.
Three lectins have been isolated from an extract of mistletoe (Viscum album) by affinity chromatography on partially hydrolysed Sepharose and human immunoglobulin- Sepharose. The lectins differ in molecular weight and sugar specificity (lectin I, mol.wt. 11500, D-galactose-specific; lectin II, mol.wt. 60000, both D-galactose- and N-acetyl-D-galactosamine-specific; lectin III, mol. wt. 50000, N-acetyl-D-galactosamine-specific). All three lectins react with human erythrocytes without specificity for the A, B, and O blood groups. In contrast with abrin and ricin the mistletoe lectins cannot be divided into "toxins" and "haemagglutinins".
通过在部分水解的琼脂糖和人免疫球蛋白 - 琼脂糖上进行亲和层析，从槲寄生（欧洲槲寄生）提取物中分离出了三种凝集素。这些凝集素在分子量和糖特异性方面存在差异（凝集素I，分子量11500，对D - 半乳糖具有特异性；凝集素II，分子量60000，对D - 半乳糖和N - 乙酰 - D - 半乳糖胺均具有特异性；凝集素III，分子量50000，对N - 乙酰 - D - 半乳糖胺具有特异性）。所有这三种凝集素都能与人红细胞发生反应，且对A、B和O血型没有特异性。与相思子毒素和蓖麻毒素不同，槲寄生凝集素不能分为“毒素”和“血凝素”。
