[Influence of the cell organelle volume on the kinetics of transmembrane transport].

Conditions are considered under which the volume of an organelle rapidly achieves a quasi-equilibrium value depending on the osmotic pressure in solution. The influence of rapid changes in the volume on the transmembrane ion transport was analysed. With account for these changes the apparent kinetic parameters Kmb and Vmb were shown to differ considerably from the true Km and Vm. In the presence of the active ion transport from an organelle into the medium the rate of release increases autocatalitically with the concentration of a permeating ion in the medium.