来自加利利链霉菌MA144 - M1突变株的新蒽环类代谢产物。II. 2 - 羟基阿克拉酮及新阿克拉酮糖苷的结构
New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. II. Structure of 2-hydroxyaklavinone and new aklavinone glycosides.
作者信息
Matsuzawa Y, Yoshimoto A, Shibamoto N, Tobe H, Oki T, Naganawa H, Takeuchi T, Umezawa H
出版信息
J Antibiot (Tokyo). 1981 Aug;34(8):959-64. doi: 10.7164/antibiotics.34.959.
Four blocked mutants of aclacinomycin-producing Streptomyces galilaeus MA144-M1 produced new anthracyclinones; 2-hydroxyaklavinone, its non-esterified analog and 2-hydroxy-7-deoxyaklavinone, several new anthracyclines; 2-deoxyfucosyl-2-deoxyfucosyl-rhodosaminylaklavinone (MA144 U1), 2-deoxyfucosyl-rhodosaminylaklavinone (MA144 U2) and five aklavinone glycosides devoid of amino sugar, designated as MA144 U5, U6, U7, U8 and U9.
阿克拉霉素产生菌加利利链霉菌MA144-M1的四个阻断突变体产生了新的蒽环酮类化合物；2-羟基阿克拉酮、其非酯化类似物和2-羟基-7-脱氧阿克拉酮，几种新的蒽环类抗生素；2-脱氧岩藻糖基-2-脱氧岩藻糖基-红霉胺基阿克拉酮（MA144 U1）、2-脱氧岩藻糖基-红霉胺基阿克拉酮（MA144 U2）以及五种不含氨基糖的阿克拉酮糖苷，分别命名为MA144 U5、U6、U7、U8和U9。
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