破伤风毒素对大鼠海马切片γ-氨基丁酸释放的体外效应
In vitro effect of tetanus toxin on GABA release form rat hippocampal slices.
作者信息
Collingridge G L, Thompson P A, Davies J, Mellanby J
出版信息
J Neurochem. 1981 Oct;37(4):1039-41. doi: 10.1111/j.1471-4159.1981.tb04492.x.
Abstract
Ca2+-dependent K+-stimulated gamma-aminobutyric acid release from rat hippocampal slices was reduced about 30% by pre-incubation of the slices with 10(4) mouse LD50/ml tetanus toxin for 3 h at 37 degrees C.
摘要
在37℃下，将大鼠海马切片与每毫升含10⁴个小鼠半数致死量的破伤风毒素预孵育3小时，可使钙离子依赖性钾离子刺激的γ-氨基丁酸从大鼠海马切片中的释放减少约30%。
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