γ-氨基丁酸拮抗剂改变视杆驱动而非视锥驱动的猫视网膜神经节Y细胞感受野中心的空间总和。
Gaba-antagonists alter spatial summation in receptive field centres of rod- but not cone-drive cat retinal ganglion Y-cells.
作者信息
Kirby A W, Schweitzer-Tong D E
出版信息
J Physiol. 1981 Nov;320:303-8. doi: 10.1113/jphysiol.1981.sp013950.
Abstract
- When Y-type cat retinal ganglion cells were driven by cones, the i.v. administration of the GABA-antagonist picrotoxin failed to alter receptive field centre size. 2. This result is in marked contrast to our previous finding that when Y-cells were driven by rods, GABA-antagonists led to specific and reversible changes in centre size. 3. These results taken together suggest that for centre signals of Y-cells, the rod and cone pathways are pharmacologically distinct.
摘要
- 当用视锥细胞驱动Y型猫视网膜神经节细胞时，静脉注射GABA拮抗剂印防己毒素未能改变感受野中心大小。2. 这一结果与我们之前的发现形成显著对比，即当用视杆细胞驱动Y细胞时，GABA拮抗剂会导致中心大小发生特定且可逆的变化。3. 综合这些结果表明，对于Y细胞的中心信号，视杆细胞和视锥细胞通路在药理学上是不同的。
相似文献
1
Gaba-antagonists alter spatial summation in receptive field centres of rod- but not cone-drive cat retinal ganglion Y-cells.γ-氨基丁酸拮抗剂改变视杆驱动而非视锥驱动的猫视网膜神经节Y细胞感受野中心的空间总和。
J Physiol. 1981 Nov;320:303-8. doi: 10.1113/jphysiol.1981.sp013950.
2
GABA-antagonists and spatial summation in Y-type cat retinal ganglion cells.γ-氨基丁酸拮抗剂与Y型猫视网膜神经节细胞的空间总和
J Physiol. 1981 Mar;312:335-44. doi: 10.1113/jphysiol.1981.sp013631.
3
Isolation of rod and cone contributions to cat ganglion cells by a method of light exchange.通过光交换法分离猫神经节细胞中视杆和视锥细胞的贡献。
J Physiol. 1976 Jan;254(3):759-73. doi: 10.1113/jphysiol.1976.sp011257.
4
The size and shape of rod and cone centres of cat retinal ganglion cells.猫视网膜神经节细胞的视杆和视锥中心的大小及形状。
Exp Brain Res. 1981;43(3-4):422-8. doi: 10.1007/BF00238386.
5
Effects of picrotoxin and strychnine on non-linear responses of Y-type cat retinal ganglion cells.印防己毒素和士的宁对Y型猫视网膜神经节细胞非线性反应的影响。
J Physiol. 1982 Mar;324:347-63. doi: 10.1113/jphysiol.1982.sp014116.
6
Effects of some amino acids (GABA, glycine, taurine) and of their antagonists (picrotoxin, strychnine) on spatial and temporal features of frog retinal ganglion cell responses.某些氨基酸（γ-氨基丁酸、甘氨酸、牛磺酸）及其拮抗剂（印防己毒素、士的宁）对蛙视网膜神经节细胞反应的空间和时间特征的影响。
Pflugers Arch. 1980 May;385(1):51-64. doi: 10.1007/BF00583915.
7
Chromatic sensitivity and spatial organization of cat visual cortical cells: cone-rod interaction.猫视觉皮层细胞的色觉敏感性和空间组织：锥体细胞与杆体细胞的相互作用
J Physiol. 1971 Mar;213(2):475-94. doi: 10.1113/jphysiol.1971.sp009394.
8
Effects of picrotoxin and strychnine on rabbit retinal ganglion cells: changes in centre surround receptive fields.印防己毒素和士的宁对兔视网膜神经节细胞的影响：中央-周边感受野的变化
J Physiol. 1978 Mar;276:299-310. doi: 10.1113/jphysiol.1978.sp012234.
9
Receptive field mechanisms of sustained and transient retinal ganglion cells in the cat.猫视网膜持续型和瞬变型神经节细胞的感受野机制
Exp Brain Res. 1975 Aug 14;23(2):113-28. doi: 10.1007/BF00235454.
10
Cancellation of rod signals by cones, and cone signals by rods in the cat retina.猫视网膜中视锥细胞对视杆细胞信号的抵消以及视杆细胞对视锥细胞信号的抵消。
J Physiol. 1976 Jan;254(3):775-85. doi: 10.1113/jphysiol.1976.sp011258.
引用本文的文献
1
GABAergic neurotransmission and retinal ganglion cell function.γ-氨基丁酸能神经传递与视网膜神经节细胞功能。
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2015 Mar;201(3):261-83. doi: 10.1007/s00359-015-0981-z. Epub 2015 Feb 6.
2
The classical receptive field surround of primate parasol ganglion cells is mediated primarily by a non-GABAergic pathway.灵长类动物伞状神经节细胞的经典感受野周围主要由一条非γ-氨基丁酸能通路介导。
J Neurosci. 2004 Apr 14;24(15):3736-45. doi: 10.1523/JNEUROSCI.5252-03.2004.
3
Effects of picrotoxin and strychnine on non-linear responses of Y-type cat retinal ganglion cells.印防己毒素和士的宁对Y型猫视网膜神经节细胞非线性反应的影响。
J Physiol. 1982 Mar;324:347-63. doi: 10.1113/jphysiol.1982.sp014116.
4
Spatiotemporal frequency responses of cat retinal ganglion cells.猫视网膜神经节细胞的时空频率响应。
J Gen Physiol. 1987 Apr;89(4):599-628. doi: 10.1085/jgp.89.4.599.
5
Voltage-dependent conductances of solitary ganglion cells dissociated from the rat retina.从大鼠视网膜分离出的单个神经节细胞的电压依赖性电导。
J Physiol. 1987 Apr;385:361-91. doi: 10.1113/jphysiol.1987.sp016497.
本文引用的文献
1
The contrast sensitivity of retinal ganglion cells of the cat.猫视网膜神经节细胞的对比敏感度。
J Physiol. 1966 Dec;187(3):517-52. doi: 10.1113/jphysiol.1966.sp008107.
2
GABA-antagonists and spatial summation in Y-type cat retinal ganglion cells.γ-氨基丁酸拮抗剂与Y型猫视网膜神经节细胞的空间总和
J Physiol. 1981 Mar;312:335-44. doi: 10.1113/jphysiol.1981.sp013631.
3
Quantitative aspects of sensitivity and summation in the cat retina.猫视网膜中敏感性和总和的定量研究
J Physiol. 1968 Sep;198(1):17-38. doi: 10.1113/jphysiol.1968.sp008591.
4
Another tungsten microelectrode.另一根钨微电极。
Med Biol Eng. 1972 Jul;10(4):510-5. doi: 10.1007/BF02474199.
5
Quantitative analysis of retinal ganglion cell classifications.视网膜神经节细胞分类的定量分析。
J Physiol. 1976 Nov;262(2):237-64. doi: 10.1113/jphysiol.1976.sp011594.
6
The involvement of gamma-aminobutyric acid in the organization of cat retinal ganglion cell receptive fields. A study with picrotoxin and bicuculline.γ-氨基丁酸在猫视网膜神经节细胞感受野组织中的作用。用印防己毒素和荷包牡丹碱进行的一项研究。
J Gen Physiol. 1976 Oct;68(4):465-84. doi: 10.1085/jgp.68.4.465.
7
Cone signals in the cat's retina.猫视网膜中的视锥信号。
J Physiol. 1977 Jul;269(2):273-96. doi: 10.1113/jphysiol.1977.sp011902.
8
Cat cones have rod input: a comparison of the response properties of cones and horizontal cell bodies in the retina of the cat.猫的视锥细胞有视杆细胞输入：猫视网膜中视锥细胞和水平细胞体反应特性的比较。
J Comp Neurol. 1977 Mar 1;172(1):109-35. doi: 10.1002/cne.901720106.
9
Eye movements in paralyzed cats induced by drugs and sympathetic stimulation.药物和交感神经刺激诱导的瘫痪猫的眼球运动。
Vision Res. 1979;19(11):1249-52. doi: 10.1016/0042-6989(79)90191-3.
10
The inner plexiform layer in the retina of the cat: electron microscopic observations.猫视网膜内丛状层：电子显微镜观察
J Neurocytol. 1979 Jun;8(3):295-329. doi: 10.1007/BF01236124.
Zotero 插件