Continuous electrocardiographic recording (Holter method) during indapamide treatment: a study of 40 cases.

In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had an incidence of more than 1% extrasystoles. However, in the other 2 patients who presented with an incidence of more than 1% extrasystoles the incidence of extrasystoles rose.