Madewell J E, Ragsdale B D, Sweet D E
Radiol Clin North Am. 1981 Dec;19(4):715-48.
The interface between tumor and bone that is displayed radiographically is a zone of cellular activity. Its radiographic appearance represents the summation of bone lysis and production. This activity and the radiographic details of the resultant margin are an index of the biologic activity of a lesion. The anatomic site and extent of the lesion can be assessed by radiographs and special imaging techniques. Careful analysis of these patterns, when integrated with clinical data, enhances diagnosis, patient management, and therapy.
影像学显示的肿瘤与骨之间的界面是一个细胞活动区域。其影像学表现代表了骨溶解和骨生成的总和。这种活动以及由此产生的边缘的影像学细节是病变生物活性的一个指标。病变的解剖部位和范围可以通过X线片和特殊成像技术进行评估。当这些模式与临床数据相结合进行仔细分析时，可提高诊断、患者管理和治疗水平。
