Albrechtsen D, Bergan A, Gjone E, Nygaard K, Flatmark A
Scand J Gastroenterol. 1981;16(6):825-31. doi: 10.3109/00365528109181010.
Chronic ulcerative colitis was treated by elective colectomy in 158 patients. Proctocolectomy and ileostomy was performed in 140 patients and colectomy and ileorectal anastomosis (CIRA) in 18 patients. The operative mortality was 2.5%, and postoperative complications, mostly infections, occurred in 38%. Within a 2-year postoperative period another 1.9% of the patients died, and late complications occurred in 18%. Colorectal carcinoma was present at the time of colectomy in 5.1% and developed some years later in another two patients primarily operated on with CIRA. Half of the cancer patients died of malignancy. Most extracolic complications, present in 25% of patients before colectomy, regressed or disappeared after operation. Half of the patients operated on with CIRA needed to have their rectum removed within a few years because of cancer or proctitis, and few of the rest had lasting relief of symptoms.
158例慢性溃疡性结肠炎患者接受了选择性结肠切除术治疗。140例行全结肠直肠切除术和回肠造口术,18例行结肠切除术和回肠直肠吻合术(CIRA)。手术死亡率为2.5%,术后并发症发生率为38%,主要为感染。术后2年内,另有1.9%的患者死亡,晚期并发症发生率为18%。结肠切除术时发现结直肠癌的患者占5.1%,另有2例最初接受CIRA手术的患者在数年后发生了结直肠癌。半数癌症患者死于恶性肿瘤。25%的患者在结肠切除术前行存在的大多数结肠外并发症在术后消退或消失。接受CIRA手术的患者中有一半因癌症或直肠炎在数年内需要切除直肠,其余患者中很少有人症状得到持久缓解。