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跟腱黄色瘤

Xanthomas of the Achilles tendon.

作者信息

Karaharju E, Paavolainen P, Holmström T, Nikkari T

出版信息

Ann Chir Gynaecol. 1981;70(3):116-9.

PMID:7325578
Abstract

The patients with xanthomas bilaterally in the Achilles tendons associated with type-II hyperbetalipoproteinaemia are reported. Both patients had elevated serum cholesterol, normal or slightly elevated serum triglycerides and an electrophoretic pattern of elevated beta and pre-beta lipoproteins. Subtotal resection of the tumours was found to be satisfactory in both patients with less risk of complications when compared with the earlier methods reported with total excision and reconstruction of the defect with fascial grafts. The early recognition and evaluation of the patients with hyperbetalipoproteinaemia is important because it is associated with an increased incidence of atheromatous coronary disease, often manifestated at an early age. That is why surgical interventions of tendon xanthomas must be connected with adequate medical treatment of the basic disorder in lipid metabolism

摘要

报告了双侧跟腱出现黄色瘤并伴有II型高β脂蛋白血症的患者。两名患者血清胆固醇均升高,血清甘油三酯正常或略有升高,β和前β脂蛋白电泳图谱升高。与早期报道的完全切除并用筋膜移植修复缺损的方法相比,发现对两名患者进行肿瘤次全切除效果令人满意,并发症风险更低。对高β脂蛋白血症患者进行早期识别和评估很重要,因为它与动脉粥样硬化性冠状动脉疾病的发病率增加有关,且常于早年发病。这就是为什么肌腱黄色瘤的手术干预必须与脂质代谢基本紊乱的适当药物治疗相结合。

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