De Santo N G, Capodicasa G, Capasso G, Giordano C
Artif Organs. 1981 Nov;5(4):409-14. doi: 10.1111/j.1525-1594.1981.tb04023.x.
By combining: a) nitroprusside (4.5 mg/L); b) dextrose concentration of 42.5 gm/L; c) dialysate temperature of 42 degrees C and d) dialysate flow rates of 3.5 L/hour in seven uremic subjects on CAPD, it was possible to increase peritoneal urea clearance up to 35.6 +/- 3.8 ml/min/1.73 m2 (range 30.3 to 42.2). This effect in six out of seven cases was associated with a fall in blood pressure and an increase in heart rate. This study is the first which deals with a combination of these factors and demonstrates that this approach is easy to handle, does not require the use of mechanical devices, and is available at any bedside.
通过在7名接受持续性非卧床腹膜透析（CAPD）的尿毒症患者中联合使用：a）硝普钠（4.5毫克/升）；b）葡萄糖浓度为42.5克/升；c）透析液温度为42摄氏度；d）透析液流速为3.5升/小时，有可能将腹膜尿素清除率提高到35.6±3.8毫升/分钟/1.73平方米（范围为30.3至42.2）。7例中有6例出现这种效果的同时伴有血压下降和心率增加。本研究首次探讨了这些因素的联合应用，并证明这种方法易于操作，无需使用机械设备，且在任何床边均可实施。
