核心颗粒的稳定性关键取决于少数末端核苷酸。

Core particle stability critically depends upon a small number of terminal nucleotides.

作者信息

Erard M, Pouyet J, Mazen A, Champagne M, Daune M

出版信息

Biophys Chem. 1981 Oct;14(2):123-33. doi: 10.1016/0301-4622(81)85013-2.

Abstract

An apparently homogeneous population of core particles is in fact composed of three subpopulations which behave differently when exposed to a high concentration of ethidium bromide or to 0.6 M NaCl. These subspecies have been identified by the use of several techniques, viz., electron microscopy, sedimentation velocity and circular dichroism. The electrophoretic analysis of their DNA leads to the conclusion that core particle stability critically depends upon a small number of terminal nucleotides.

摘要

表面上看似均一的核心颗粒群体实际上由三个亚群体组成，当暴露于高浓度溴化乙锭或0.6M氯化钠时，它们的行为有所不同。这些亚群体已通过几种技术得以鉴定，即电子显微镜、沉降速度和圆二色性。对其DNA的电泳分析得出结论，核心颗粒的稳定性关键取决于少数末端核苷酸。