Eckardt M J, Matarazzo J D
J Clin Neuropsychol. 1981 Oct;3(3):257-69. doi: 10.1080/01688638108403129.
Seven measures of neuropsychological functioning, the resulting Impairment Index described by Halstead, and Trails A and B were administered to drug-free alcoholic inpatients (n=91) within 7 days of their last drink and again 17 days later. Nonalcoholic medical inpatients (n=20) with similar education, age, and socioeconomic characteristics were also given these tests twice, with 2 to 3 weeks separating the test administrations. Both groups showed levels of mild to moderate impairment on the first testing and were judged to have stable brain functioning between the first and second testing. Significant Pearson's coefficients of correlation between test-retest scores indicated similar psychometric reliabilities in both groups. In contrast, the reliability of the tests was judged to be questionable when Halstead's binary classification of "normal" versus "abnormal" was used to classify individual patients. Consequently, and consistent with clinical experience, we urge caution in interpreting these clinical neuropsychological tests when they are administered repeatedly within a 2- to 3-week period to a single individual with stabilized brain functioning.
对91名已戒酒的酒精性肝病住院患者在其最后一次饮酒后7天内进行了7项神经心理功能测试、由霍尔斯特德描述的由此产生的损伤指数测试以及A和B连线测验,17天后再次进行测试。具有相似教育程度、年龄和社会经济特征的20名非酒精性内科住院患者也接受了两次这些测试,两次测试间隔2至3周。两组在首次测试时均表现出轻度至中度损伤水平,并且在首次和第二次测试之间被判定脑功能稳定。重测分数之间显著的皮尔逊相关系数表明两组的心理测量信度相似。相比之下,当使用霍尔斯特德的“正常”与“异常”二元分类来对个体患者进行分类时,测试的信度被判定存在问题。因此,与临床经验一致,我们敦促在对脑功能稳定的个体在2至3周内重复进行这些临床神经心理测试时,要谨慎解释测试结果。