Campbell J R, Godsall J W, Bloch S
Prostate. 1981;2(4):417-23. doi: 10.1002/pros.2990020409.
A review of 10 years experience with prostatic carcinoma was undertaken with a search for neurologic complications. An unusual case presenting with symptoms of hemiplegia is reviewed. Of 154 charts, 90 provided adequate clinical information for complete analysis. Nineteen cases with neurologic complications were found and were restricted entirely to advanced (stages C and D) disease. Thirty-seven percent of patients with advanced disease developed neurologic complications. The most frequent complaints were related to organic brain syndrome, paraplegia, and radiculopathy. Eight patients developed peripheral nerve or spinal cord injury related to metastatic disease. Five patients suffered metabolic or paraneoplastic complications; three patient's symptoms related to central or epidural metastases and two patients developed neurologic symptoms related to complications of therapy. All neurologic symptoms improved given appropriate diagnosis and treatment. A brief review of the literature is included emphasizing the diverse nature of neurologic complications in this common neoplasm.
我们回顾了10年的前列腺癌治疗经验，以寻找神经并发症。本文回顾了1例以偏瘫症状就诊的罕见病例。在154份病历中，90份提供了足够的临床信息用于完整分析。发现19例有神经并发症的病例，且均为晚期（C期和D期）疾病。37%的晚期疾病患者出现神经并发症。最常见的症状与器质性脑综合征、截瘫和神经根病有关。8例患者出现与转移性疾病相关的周围神经或脊髓损伤。5例患者出现代谢或副肿瘤并发症；3例患者的症状与中枢或硬膜外转移有关，2例患者出现与治疗并发症相关的神经症状。给予适当的诊断和治疗后，所有神经症状均有改善。本文还简要回顾了文献，强调了这种常见肿瘤中神经并发症的多样性。
