Bredberg A, Lambert B, Swanbeck G, Thyresson-Hök M
Acta Derm Venereol. 1977;57(5):389-91.
Human fibroblasts were exposed to tritium-labelled 8-methoxypsoralen (8-MOP) and longwave ultraviolet (UVA) light in vitro. The proportions of photochemically bound 8-MOP in the nucleus and cytoplasm were studied by autoradiography. The results show that UVA-irradiation of the cells in the presence of 8-MOP gives rise to a significant dose-dependent binding of 8-MOP in the cell nucleus.
在体外将人成纤维细胞暴露于氚标记的8-甲氧基补骨脂素（8-MOP）和长波紫外线（UVA）下。通过放射自显影术研究了8-MOP在细胞核和细胞质中的光化学结合比例。结果表明，在8-MOP存在的情况下对细胞进行UVA照射会导致8-MOP在细胞核中产生显著的剂量依赖性结合。
